PINEL, Traité Médico-Philosophique sur l'Aliénation mentale ou la Manie, 1801

First edition.
"Pinel was among the first to treat the insane humanely; he dispensed with chains and placed his patients under the care of specially selected physicians. Garrison considered the above book one of the foremost medical classics, giving as it did a great impetus to humanitarian treatment of the insane. Pinel founded the french school of psychiatry" (Garisson).